第1章 你所需的技巧 THE SKILLS YOU NEED
1.1 本書的目標
The Goal of This book
1.2 反應機構是你的成功之鑰
Mechanisms Are Your Keys to Success
第2章 離子反應機構簡介 INTRO TO IONIC MECHANISMS
2.1 彎曲箭
Curved Arrows?? ?
2.2 基本步驟
The Basic Moves
2.3 基本步驟的組合
Combining the Basic Moves
第3章 親電子芳香取代反應 ELECTROPHILIC AROMATIC SUBSTITUTION
3.1 鹵化和路易士酸扮演的角色
Halogenation and the role of Lewis Acids?? ?
3.2 硝化
Nitration
3.3 夫里德耳－夸夫特烷化和醯化反應
Friedel-Crafts Alkylation and Acylation
3.4 磺化
Sulfonation
3.5 修改親核基的活性
Modifying the Nucleophilicity of the Nucleophile
3.6 預測引導效應
Predicting Directing Effects
3.7 判斷活化基和去活化基
Identifying Activators and Deactivators?? ?
3.8 立體障礙效應的預測與運用
Predicting and Exploiting Steric Effects?? ?
3.9 合成策略
Synthesis Strategies?? ?
第4章 親核芳香取代反應 NUCLEOPHILIC AROMATIC SUBSTITUTION
4.1 親核芳香取代反應的條件
Criteria for Nucleophilic Aromatic Substitution?? ?
4.2 SNAR反應機構
SNAr Mechanism?? ?
4.3 脫去—加成反應
Elimination-Addition?? ?
4.4 反應機構策略
Mechanism Strategies?? ?
第5章 酮和醛 KETONES AND ALDEHYDES
5.1 酮和醛的製備
Preparation of Ketones and Aldehydes
5.2 羰基的穩定性與活性
Stability and Reactivity of the Carbonyl
5.3 氫親核基
H-Nucleophiles
5.4 氧親核基
O-Nucleophiles
5.5 硫親核基
S-Nucleophiles
5.6 氮親核基
N-Nucleophile
5.7 碳親核基
C-Nucleophiles
5.8 黃金法則的重要例外
Some Important Exceptions to the Rule
5.9 如何處理合成問題
How to Approach Synthesis Problems
第6章 羧酸衍生物 CARBOXYLIC ACID DERIVATIVES
6.1 通則
General Rules
6.2 醯基鹵
Acyl Halides
6.3 酸酐
Anhydrides
6.4 酯
Esters?? ?
6.5 醯胺和?
Amides and Nitriles
6.6 合成問題
Synthesis Problems
第7章 烯醇和烯醇鹽 ENOLS AND ENOLATES
7.1 酮－烯醇互變異構化反應
Keto-Enol Tautomerism
7.2 烯醇的反應
Reactions Involving Enols
7.3 製備烯醇鹽
Making Enolates
7.4 鹵仿反應
Haloform Reactions
7.5 烯醇鹽的烷化
Alkylation of Enolates
7.6 醇醛反應和醇醛縮合
Aldol Reaction and Aldol Condensation
7.7 克萊森縮合
Claisen Condensation
7.8 去羧提供了一些有用的合成技巧
Decarboxylation Provides Some Useful Synthetic Techniques
7.9 麥可反應
Michael Reactions
第8章 胺 AMINES
8.1 胺和醯胺的親核性和鹼性
Nucleophilicity and Basicity of Amines and Amides
8.2 藉由SN2反應來製備胺
Preparation of Amines through SN2 Reactions
8.3 用還原胺化反應製備胺
Preparation of Amines through Reductive Amination
8.4 從醯胺製備胺
Preparation of Amines from Amides
8.5 胺的醯化
Acylation of Amines
8.6 胺與亞硝酸的反應
Reactions of Amines with Nitrous Acid
8.7 芳香基重氮鹽
Aromatic Diazonium Salts
習題解答
重要名詞英中對照
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